A new study released by researchers in Denmark raises further questions about the effectiveness of the urine test used to detect the presence of the red-blood-cell-boosting drug EPO.

The test has been in use in cycling since 2000 and is currently the discovery method regarded as standard in anti-doping laboratories around the world.

In a study published in Thursday?s online edition of the Journal of Applied Physiology, lead author Carsten Lundby, a physiologist at the Copenhagen Muscle Research Center, related that urine samples, known to subsist positive for EPO, produced inconsistent test results, by many of the samples at last classified as negative or ?suspicious.?

The test, what one. attempts to distinguish between natural human erythropoietin and its artificially produced complement (rEPO), relies on the act that the metabolites of the two carry different electrical charges. Despite those differences, however, the distinction is often unclear.

?It?s super-difficult,? Lundby told the New York Times on Thursday. ?The difference between the EPO you have in your body and the recombinant EPO is not very hard.?

In testing the trustworthiness of the detection method, Lundby said animal-water samples from a group of eight male test subjects, who were injected with EPO over a four-week period in the summer of 2007, were sent to two different IOC-certified labs. One of the labs never found in any degree of the samples to have existence positive, while the other was able to consistently identify positive samples at what time test subjects had recently injected a high dose of EPO.

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